The original research articles published in medical journals contribute to the advancement of patient care, clinical practice, and scientific comprehension.

Instructions

• The manuscript should be in the English language in a Word file with images and tables inserted at the end of the manuscript (cited at the required places in the manuscript body).

• The title should be descriptive and concise.

• The tables should be limited to ≤6 and figures should be ≤5 in number.

• Make sure to add a CONSORT diagram in the “Materials and Methods” section if two or more groups are compared or studied (this figure does not count towards the number of tables and figures)

• The font type should be ‘Times New Roman’ with a font size of ‘12’.

• The document should have the A4 paper size, double spacing (2.0), and normal margins.

• Maximum length: 3000 words (excluding abstract, references, figures, and tables)

The manuscript should have the following headings:

• Title page

• Abstract

• Introduction

• Materials and Methods

• Results

• Discussion

• Conclusion

• Conflict of interest

• Data availability statement

• Ethics statement

• Acknowledgement

• References

• Tables

• Figures

• Supplementary information

Title Page
The title page should be formatted as follows:

1. Present the title in as few words as possible that correctly represent the manuscript's content.

• The research design should be included in the subtitle for clinical trials, systematic reviews, and meta-analyses. For example, “The assessment of A versus B: a randomized controlled trial.”

• The title should be written in capitalize each word. Try to avoid specialized abbreviations in the title. Articles, conjunctions, and prepositions should not be capitalized.

• Place the title centrally aligned and bold with a font size of 14.

• This should be followed by author(s) name(s) and affiliations as given below.

2. The Authors’ information should be written as follows:

• Author's last name followed by initial words of first name (eg, Sharma AL)

• Separate multiple authors by comma (eg, Sharma ALa, Mathur Mb, Chawla KP)

• In the case of a collaboration group, the group's name will be represented as the authors' name. The full list of authors can be included in the “Acknowledgment” section of the paper.

• The affiliation of each author should also be listed (that includes department, university, and organization) along with the location (city/province, state, and country). The minimum criteria for an address are the current institute, city and country.

• ORCIDs must be included for the authors, if available.

3. The corresponding author should also be listed separately on the title page as he/she will be the primary author in contact with the journal during the editorial process. Only one corresponding author can be designated as the corresponding author. The name, address, telephone number, and email address of the corresponding author must be included in the details.

Abstract

• The abstract will be placed on the new page separately. Briefly reflect the contents of the manuscript in the abstract in no more than 250 words.

• Do not cite the references in the abstract.

• In the case of randomized controlled trials, the CONSORT extension for abstract must be used.

The abstract must include the sub-headings as follows:

• Background

• Materials and Methods

• Results and discussion

• Conclusion

• Trial registration (in case of human healthcare intervention; trial registry and trial registration number should be mentioned)

Keywords: Provide a maximum of 6 keywords at the end of the abstract.
Introduction
Start it immediately after the abstract and cover the importance of your study by collecting information from different relevant articles and cite them in the form of Arabic numerals in superscripts after the decimal. Also, state the rationale behind your study. Do not exceed more than 500 words.
The introduction section should explain the purpose and basis of the study (background information of study), and its aim (why this study was initiated in the first place).

Materials and Methods
Start it immediately after the introduction. The following information should be included in this section:

• the study design and objectives of the study

• brief information on participant population, inclusion and exclusion criteria, and description of the characteristics (or description of the material)

• describe the processes, interventions, and comparators. The names of the generic drugs (brand name in parentheses) should be used in case of any drug intervention.

• a brief description of the statistical analysis type.

• mention whether or not the clinical methods were approved by your country's Ethics Committee for Human Experimentation or are in compliance with the 1975 Helsinki Declaration.

Results

• The findings from the research are to be presented in this section.

• The primary and secondary outcomes measured should be included. This section can be divided into accurate and concise subheadings.

• The results of the statistical analysis should be explained in the text; tables and figures should be included in this section. The tables and figures should have a captioned title which can be cited here and added at the end of the manuscript.

Discussion

• The findings obtained from the research should be interpreted in this section, along with references cited to provide logical proof or comparison.

• This section should include paragraphs on the hypothesis, clinical relevance, and proof in comparison with other studies, the advantages or strengths of the study and its limitations, and the future perspective of the research.

Conclusion
Clearly state the main conclusion of the research and its relevance to humans. A short paragraph will be sufficient.

Conflict of Interest
This section will include all the financial or non-financial conflicts of interest. In case of no conflict of interest, a statement will be added here.

Data Availability Statement

• The research papers must include the “Data availability statement” in their article.

• The accession number (a number given by the public repository after data storage) should be added to the data availability statement.

Ethics Statement
The studies including human participants, data, or tissue must include the ethics statement, which will include a statement on ethics approvals and consent along with the name of the ethics committee that approved the study.
In the case of animal-based intervention (where animals are used for testing), the consent of the animal owner must include the ethics statement for the committee’s approval or consent statement.

Acknowledgement
This section will include the authors or anyone who contributed towards the research work or article who is not included in authorship including persons who provided professional writing services or materials. If there’s nobody to acknowledge, “Not Applicable” should be added.

References
References should be numbered sequentially in the order in which they first appear in the text. The references in text, tables, and legends should be given in Arabic numerals in superscript form.
Prefer the following format for references in the list:

Journals
Author(s). Article title. Journal Name. Year;vol(issue no.): inclusive pages. doi (if available)
Use "et al." in the case of >6 authors. For example, Sharma A, Verma JP, Sikander A Jr, et al. Article title. Journal Name. Year;vol(issue no.): inclusive pages. doi (if available)

Books
Author(s). Book Title. Edition number (if it is the second edition or above). City, State (or Country) of publisher: Publisher’s name; copyright year.

Website
Author (or, if no author is available, the name of the organization responsible for the site). Title (or, if no title is available, the name of the organization responsible for the site). Name of the website. Published/Updated [date]. Accessed [date]. URL.
For detailed formatting styles of different sources, please use the AMA reference guide.